OUR ACTIVE INGREDIENTS

Collagen is the most abundant structural protein in the human body. As a source of protein, it contributes to the maintenance of normal bone and the growth and maintenance of muscle mass.

We include 5g of Hydrolysed Marine Collagen Peptides. This is a research-informed dose to support structural integrity and bone mass, while being manageable daily without stomach upset. The hydrolysed peptide form ensures the protein is pre-broken down for maximum absorption.

Creatine is the body's primary molecule for rapid energy regeneration. When combined with regular resistance training, a daily 3g intake is scientifically proven to enhance muscle strength in adults over the age of 55 by increasing the availability of cellular fuel.

We use 3g of Micronized Creatine Monohydrate. We strictly adhere to this research-informed dosage as it is sufficient to saturate muscle stores safely without the bloating or stomach upset common with high dose loading phases. We chose the micronized form because it dissolves better in liquid and is easier for the stomach to digest.

Vitamin D functions as a pro-hormone, regulating calcium absorption. This regulation contributes to normal blood calcium levels and the maintenance of normal muscle function. Crucially, it helps reduce the risk of falling associated with poor balance, coordination and muscle weakness in women 55+.

We use 800 IU (20 µg) of Vitamin D3. The standard baseline NRV is increasingly recognized by European physicians as insufficient for older adults, particularly those living in northern climates. We utilize a targeted 400% NRV dose to provide the modern, physician-recommended boost required for optimal calcium absorption while strictly avoiding excessive levels. We use Cholecalciferol (D3) as it is the bioactive form naturally produced by the skin, far superior to D2.

While Vitamin D helps absorb calcium, Vitamin K2 helps direct it. It acts as an essential helper molecule for proteins that contribute to the maintenance of normal bone. Emerging research highlights the synergy between D3 and K2 in optimizing skeletal integrity in ageing adults.

We use 150 µg of Vitamin K2 as Menaquinone-7 (MK-7). Informed by landmark research, we utilize a 200% NRV dose to provide the high-potency support required to direct calcium into the bone matrix and away from your arteries. This specific amount goes beyond standard daily minimums to ensure there is enough active MK-7 to optimize both skeletal strength and cardiovascular vitality. We use the MK-7 form because it stays active in the body for days, unlike synthetic MK-4 which clears rapidly.

Calcium is the essential mineral foundation of the skeletal system. Beyond its authorized role in maintaining normal bone, it is critical for normal muscle function and neurotransmission (the signaling between brain and body).

We selected 250 mg of Calcium Citrate. We provide this moderate 31% NRV top-up dose to support bone density while maintaining a healthy nutritional balance alongside your dietary intake. This precise amount is designed to provide essential structural support without the risks associated with large, concentrated doses. We use the Citrate form because it absorbs well even with low stomach acid, unlike cheaper carbonates.

Vitamin C is an essential helper molecule for the enzymes that build collagen. It contributes to normal collagen formation for the normal function of bones, cartilage, and skin. Additionally, it protects cells from oxidative stress.

We use 250 mg of Calcium Ascorbate. We use 313% NRV to provide the saturation levels required for collagen synthesis and whole-body antioxidant defense. This potency provides a targeted boost beyond daily minimums, using buffered calcium ascorbate to ensure the higher dose remains exceptionally gentle on the stomach, without exceeding the body's absorption limits per serving. We selected this buffered form (bound to calcium) because it is non-acidic and far gentler on the stomach than standard ascorbic acid.

Thiamine (B1), Riboflavin (B2), Niacin (B3), and Pantothenic Acid (B5) contribute to normal energy-yielding metabolism, effectively converting nutrients into the fuel needed for muscle and brain function.

We include these at physiological doses to provide consistent enzymatic support while avoiding the itching, redness, and nausea often triggered by mega-doses. We use active coenzyme forms like Riboflavin 5'-Phosphate so your body can utilize these nutrients immediately for energy production.

Vitamin B6 is essential for producing neurotransmitters, the chemical messengers that allow your brain cells to "talk" to one another. These include serotonin (which regulates your mood and sense of well-being) and dopamine (which supports your motivation and focus). By supporting these messengers, Vitamin B6 contributes to the reduction of tiredness, normal psychological function, and the regulation of hormonal activity.

We use 3 mg of Pyridoxal-5-Phosphate (P-5-P). Informed by landmark longevity research, we provide a high-potency 214% NRV dose of active P-5-P to support cognitive and hormonal health. This level is carefully calibrated to offer optimized physiological support while strictly avoiding the neuropathy (nerve sensitivity) risks associated with excessive doses of the standard synthetic pyridoxine. We use P-5-P because it is the ready-to use, active coenzyme form, requiring no liver conversion.

Folate is required to recycle homocysteine, a natural byproduct that can rise with age. If left unmanaged, high levels of this byproduct may impact the delicate structures of your heart and brain. Folate converts it back into useful nutrients. Folate also contributes to normal psychological function, blood formation, and the reduction of tiredness and fatigue.

We use 400 µg of 5-MTHF. Informed by landmark longevity research, we utilize this 200% NRV dose to support healthy homocysteine metabolism. This potency ensures optimal metabolic activity where lower doses often fall short, providing a safe and effective level for sustained cardiovascular and psychological support. We strictly use the methylated form (5-MTHF) because it bypasses the MTHFR gene mutation that prevents many people from processing standard folic acid.

Absorption efficiency of B12 decreases significantly with age due to reduced stomach acid. It contributes to normal energy-yielding metabolism, red blood cell formation, and the normal functioning of the nervous system.

We use 500 µg of Methylcobalamin. While this dose is significantly higher than the NRV, this high potency dose is informed by research and specifically chosen to bypass age-related absorption gaps where standard doses often fail. By creating a concentration gradient, this allows the essential amount of B12 your body needs to seep directly through the intestinal wall. This approach is exceptionally safe as Vitamin B12 has no known toxicity, providing the mandatory foundation to balance our high-dose folate for nervous system support. We chose Methylcobalamin as it is the bio-identical form found in nature, offering better retention than synthetic cyanocobalamin.

Chromium contributes to the maintenance of normal blood glucose levels, supporting steady energy regulation and metabolic health.

We use 20 µg of Chromium Picolinate. We chose this safe maintenance dose (50% NRV) to support steady glucose metabolism, without interfering with other mineral absorption.. We use the Picolinate form because it is significantly more stable and bioavailable than standard chromium salts.

Selenium contributes to normal thyroid function (the master regulator of metabolism) and the protection of cells from oxidative stress.

We use 40 µg of Selenium Yeast. Our 73% dose provides essential antioxidant and thyroid support without accumulation. It complements your diet to maintain cellular defense while avoiding toxicity from excessive intake. We use the organic yeast form because it mimics food, allowing for superior storage in muscle tissue.

Copper supports the maintenance of normal connective tissues. Together with Manganese, it helps maintain the structural mesh that supports joints and bones.

We use 900 µg of Copper (Bisglycinate). We calibrated this dose (90% NRV) to balance our Zinc intake, preventing the copper deficiency often caused by zinc supplements. We deliberately avoid excessive amounts for long-term safety and to prevent mineral accumulation. We selected the bisglycinate form for its superior stability and absorption compared to standard sulfates.

Manganese is a trace mineral that acts as a helper molecule for enzymes involved in tissue repair. It contributes to the normal formation of connective tissue and protects cells from oxidative stress.

We use 0.5 mg of Manganese (Bisglycinate). We kept this dose moderate (35%NRV) to provide safe, long-term connective tissue support without risk of accumulation. We chose the bisglycinate form to ensure it survives digestion and is actually absorbed.

Powerful botanical for mood.

Interaction Risks. It carries complex interaction risks with common medications, including blood thinners and anti-depressants. Because Silvie Mind is a daily foundation for everyone, we excluded Saffron to avoid contraindications. While we don't believe this a good fit for everyone, Saffron is on our watchlist for future, more targeted products.

Effective adaptogen for reducing stress-related fatigue.

Lack of long-term safety data beyond 12 weeks for continuous daily use. For a lifelong foundational system like Silvie, we cannot include ingredients without proven safety over extended periods. While we don't believe this a good fit for everyone, Rhodiola rosea is on our watchlist for future, more targeted products.

Supports nerve growth factors and cognitive function.

While its safety profile is high, the current body of human evidence for cognitive maintenance is small and insufficient to justify its inclusion as a proven daily foundational ingredient. While we don't believe this a good fit for everyone, Lion's Mane is on our watchlist for future, more targeted products.

Potent neuro-precursor for brain health.

While the mechanistic science is compelling, the evidence demonstrating clear cognitive improvement in healthy older adults is currently promising but not well established and contested by EFSA. While we don't believe this a good fit for everyone, citicoline is on our watchlist for future, more targeted products.

Sirtuin pathway activation.

Human clinical evidence for substantial longevity benefits is challenging, largely due to its notoriously poor bioavailability, which makes achieving an effective dose at the cellular level difficult to establish. While we don't believe this a good fit for everyone, resveratrol is on our watchlist for future, more targeted products.

Potential for cellular energy & longevity.

The dramatic longevity benefits are predominantly observed in rodent models. The results in humans, while promising for certain metabolic markers, are currently inconclusive for overall lifespan and healthspan extension. While we don't believe this a good fit for everyone, NMN & NR are on our watchlist for future, more targeted products.

These ingredients show promise as being highly specialised "beauty from within" actives for targeted skin hydration & antioxidant defense.

These ingredients are being investigated for a dedicated skincare formulation, coming soon...